Men who chose to undergo vasectomy reversal clearly have the primary goal of becoming fathers. There is a fair amount of overlap in men desiring paternity through vasectomy reversal who are also hypogonadal, also known as having a low testosterone level. Traditional testosterone replacement treatment options such as testosterone gels, injections, and pellets decrease sperm production and have an adverse impact on a man’s ability to father children after vasectomy reversal. For that reason, clomiphene citrate has commonly been used, off-label, for the treatment of hypogonadism in a manner that does not suppress sperm production. A number of studies have been published evaluating the safety and efficacy of using this medication in men, but they have been short-term studies with treatment periods of no longer than 2 years. That is, until now. Dr.’s Parviz Kavoussi and Luke Machen, reproductive urologists at Austin Fertility & Reproductive Medicine/Westlake IVF published the longest-term study to date, following men for up to 7 years on this treatment for hypogonadism, showing a good testosterone response with minimal risks. This makes clomiphene citrate an excellent choice for men with hypogonadism who plan to undergo vasectomy reversal. The study was published in the Journal of Urology. To read the study click here…
https://www.auajournals.org/doi/10.1097/JU.0000000000000396
